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 Principal Scientist

Details
Country: USA
Location: Connecticut-Danbury/Bridgeport Ridgefield
Total applied: 41
Principal Scientist

Job Category: Biotech/R&D/Science Career Level: Experienced (Non-Manager) Our CultureAt Boehringer Ingelheim, we deliver Value through Innovation by living our fundamental principles of Lead & Learn. We have high expectations for our employees. We require employees at all levels of the organization to take initiative, stay connected, grow together, and achieve outstanding results. To enable high performance, we provide opportunities for personal growth, a collaborative and inclusive work environment, and exceptional employee benefits. We reward high achievement with recognition, opportunities and competitive pay. We hold ourselves to the highest standard of excellence and count on each other to go the extra mile in everything we do. Principal Scientist REQUIREMENTS: Ph.D. in Biochemistry, Molecular Biology, Bio-Engineering or a related field with 4-8 years postdoctoral experience. 3+ years industry experience required for Principal Scientist position. Have demonstrated expertise in the area of Antibody/Protein Engineering and Molecular Biology methods Knowledge of clinical development of antibody and antibody fragments Knowledge of novel scaffolds, multi-domain and multimeric proteins DUTIES & RESPONSIBILITIES:  Provide expertise in area of Antibody/Protein Engineering by conceptualizing and utilizing methods to generate/optimize therapeutic antibodies and proteins.   Antibody Engineering includes optimizing antibody properties for clinical use and humanization of murine antibodies. Direct and oversee experimental design and results of technicians and junior level scientists. Work with multi-disciplinary groups, such as hybridoma CRO’s, recombinant antibody discovery, protein characterization, protein expression and with disease-related matrix teams. Participate as representative on multiple project teams and contribute to defining expertise-related aspects of overall program goals. Evaluate and propose new technologies and concepts in the area of antibody, antibody fragments and scaffold proteins. Demonstrate independent thinking by proposing and implementing new experimental designs. Identify potential patentable inventions and support IP group in filing of the patents. Prepare clear technical reports, publications and oral presentations. Independently communicate results in the form of reports and or presentations. Present responsibly and defends own work at scientific meetings. May deliver updates to senior level management in context of overall project goals. Keep abreast of relevant literature and serves as resource in area of specialized expertise. Develops and maintains outside visibility. Assume responsibility for direct reports as needed including recruiting, managing, mentoring and developing scientific staff. Comply with all applicable regulations; Ensure that work performed in area of responsibility is conducted in a safe and compliant manner; Maintain proper records in accordance with SOPs and policies Corporate Site

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