Research Associate - Enzymology/Biochemistry

Novartis Institutes for BioMedical Research is Novartis' global research organization and is committed to discovering innovative medicines that cure disease and improve human health. By conducting more relevant and predictable drug discovery that can yield new and better medicines for patients, Novartis Institutes for BioMedical Research is redefining drug discovery in the post-genomic era. Over the past four years, Novartis Pharmaceuticals has had the greatest number of new molecular entities approved by the US FDA. With its broad focus on diseases for which there is a need for better medical therapies, and with over 3,000 talented, dedicated research scientists worldwide, Novartis Institutes for BioMedical Research is well-positioned to ensure Novartis maintains its strong pipeline and highly successful track record in new drug discovery. Novartis Institutes has sites in Cambridge, Massachusetts (headquarters); Basel, Switzerland; Horsham, UK; East Hanover, NJ; Vienna, Austria; Tsukuba, Japan and Emeryville, California. Novartis Institutes' Cambridge facilities encompass 950,000 square feet of laboratory and office space. Research in cardiovascular disease, oncology, infectious disease, diabetes, ophthalmology and muscle disease is headquartered in Cambridge. In addition, Cambridge is home to the following platform technologies: Global Discovery Chemistry, Functional Genomics, Developmental & Molecular Pathways, and Models of Disease Center. In order to attract and develop an exceptionally talented and committed staff, Novartis Institutes for BioMedical Research offers an innovative and comprehensive benefits package, including healthcare, insurance, savings, retirement, and work/life benefits. The Novartis Institute for Biomedical Research in Cambridge, MA is looking for a research associate within thier Oncology Group/Drug Discovery Unit. Under the supervision of a Ph.D. scientist, the candidate will carry out the following activities: enzymatic assay development, medium throughput screening and IC50 determination, data processing and management, protein characterization and mechanistic studies. The job will predominantly focus on early discovery processes and will involve frequent collaborations with our Lead Discovery Scientists and Medicinal Chemists. The position requires excellent communication and collaboration skills. The ideal candidate will be self-motivated, collaborative, and able to multitask effectively.Qualifications MS with strong Biochemistry/Enzymology training and 0-3 years (or BS in Biochemistry with 5+ years) industrial experience A good understanding of biochemical modification of proteins, biochemical assay development, small molecule inhibitor characterization, enzyme kinetic characterization and mechanistic studies. Strong ability to grasp new scientific concepts, implement new assay technologies, and develop new biochemical assays to support drug discovery programs Good computer skills and familiarity with Excel Fit and other graphics Highly motivated and hard-working individual. Plus factors: some knowledge of chemical structures, intensive training in enzyme kinetics, experience in biochemistry/enzymology support for hit validation and lead optimization phases Novartis Institutes for BioMedical Research is an equal opportunity employer committed to embracing and leveraging diverse backgrounds. M/F/D/V Job ID: 37542BR