Scientist I, Preparative Chromatography

Scientist I, Preparative Chromatography Department/Division: Biotech/R&D/Science Job Type: Full Time, Employee Company: Vertex Pharmaceuticals Inc. Location: US-MA-Boston Job Reference Id: 1219   Description: Posting Title: Scientist I, Preparative Chromatography Location: Cambridge, MA Department: Chemical Development Classification: R&D/Science Required Travel: 10% Required Education: PhD, MS or BS Relocation: Yes Vertex Pharmaceuticals Incorporated is a global biotechnology company committed to the discovery and development of breakthrough small molecule drugs for serious diseases. The Company's strategy is to commercialize its products both independently and in collaboration with major pharmaceutical companies. Vertex's product pipeline is focused on viral diseases, inflammation, autoimmune diseases, cancer, pain and bacterial infection. Job Summary: Vertex is seeking a talented individual to join our Chemical Development group in Cambridge, MA. Chemical Engineering at Vertex plays a vital role in bridging the gap between new pharmaceutical discoveries and commercial products. Engineers at Vertex work in multidisciplinary scientific teams to bring basic medical discoveries to patients and physicians by applying fundamental chemistry and chemical engineering principles to new products, processes, and development technologies. The successful candidate will be a highly productive, results-oriented individual, able to generate and implement original ideas and solutions that contribute materially to the success and development of drug substance candidates. Strong communication, organization, and planning skills and a high level of technical aptitude and creativity are required for success in this position Key Responsibilities for this role include: - Development and implementation of preparative HPLC and SFC purification methods in support of API manufacture and drug substance development - Use of automated screening and method development technologies for rapid identification and implementation of purification methodologies and turnaround of purified compound - Independent coordination and prioritization of preparative separation activities, communication with the chemists to understand project needs, and training and education on the use of separation technologies and best practices - Responsible for the acquisition, startup, and regular maintenance of analytical and preparative separations instrumentation. Basic Qualifications - A Ph.D. degree with 0 - 3 years of academic, post-doctoral or pharmaceutical industry experience; an MS degree with 3 - 5 years of pharmaceutical industry experience; or a BS degree with 6+ years of pharmaceutical industry experience. - Experience with analytical and preparative chromatography method development and purification of small molecules via HPLC and SFC. Preference will be given to candidates with demonstrated experience in parallel method development and preparative HPLC and SFC separations - The ability to interact and collaborate within an interdisciplinary team environment comprised of organic, physical, and analytical chemists. - Proven communication (verbal and written) and interpersonal skills Apply Now