Principal Research Scientist I Pharm

Job Category: Biotech/R&D/Science Job Description:At Wyeth, we have a vision of leading the way to a healthier world. We've committed ourselves to achieving this vision by making quality, integrity and excellence the hallmarks of our business. A Fortune 500 company and global leader in pharmaceuticals, consumer healthcare, and animal healthcare products, we know that our employees are who keep us on the cutting edge of innovative discoveries and superior customer service. To sustain and enhance our leadership position in the pharmaceutical industry, we continue to recruit, develop and motivate individuals whose skills, values, and work ethic will grow and improve our business.The goal of Translational Medicine at Wyeth is to form a bridge between teams in drug Discovery and Clinical Development as means to promote the successful Bench to Bedside transition of new therapeutics. As a scientist in Translational Medicine you will identify biochemical, physiological and other relevant biomarkers/efficacy surrogates for use in early clinical trials as well as in animal models of autoimmune disease. You will initiate, lead, and supervise focused discovery, validation and implement studies of biomarkers research in support of drug discovery programs. You will participate in teams that form strategies, tactics for biomarkers discovery, and implementation in rheumatic disease drug discovery programs. You will also work closely with the Translational Medicine group in Scotland, UK via joint Research Collaborations towards biomarker discovery, validation and implementation. You will maintain strong scientific publications, presentations and engagements in professional forums, symposia, etc. The Translational Medicine Scientist will evaluate the potential utility of relevant compounds transitioning to Discovery for use against targeted disease indications. You will participate on Therapeutic Area Research Teams to advise on the selection of patient groups and/or volunteer models for initial indication of efficacy in humans. As a member of the Translational Medicine team for a particular therapeutic, you will be responsible for development, execution and oversight of biomarker activities in early clinical studies. Also, you will act as an advisor to Clinical R&D in recommending biomarker strategies and applications in late-stage clinical trials. You will be responsible for review of the published literature as well as other sources of information to provide team members with timely summaries and critical evaluations of advances in basic and clinical understanding of rheumatic diseases. You will propose and initiate action plans in emerging technologies related to diagnosis and treatment of rheumatic diseases. This position requires an MD and/or PhD degree in a relevant science discipline with a minimum of 5 years professional experience in disease-oriented research. A thorough knowledge of current clinical and scientific literature related to disease mechanisms in autoimmune disease is essential. Incumbent should have a solid record of publications and achievement in an academic or industrial setting and experience with the use of biomarkers or experimental approaches to drug development in highly desirable. *Level and title will be commensurate with the experience and education of the selected candidate.Relocation assistance is available.Wyeth offers competitive compensation and benefits programs, including child-care subsidies, flex-time, business casual attire, educational assistance and professional development programs. For more information and to apply online, please visit us at: www.wyeth.com/careers Wyeth is an Equal Opportunity Employer, M/F/D/V. Search Firm Representatives: Please Read Carefully. Wyeth is not seeking assistance or accepting unsolicited resumes from search firms for this employment opportunity. Regardless of past practice, all resumes submitted by search firms to any employee at Wyeth via-email, the Internet or directly to hiring managers at Wyeth in any form without a valid written search agreement in place for that position will be deemed the sole property of Wyeth, and no fee will be paid in the event the candidate is hired by Wyeth as a result of the referral or through other means. Note: Any search agreement entered into with Wyeth prior to January 2004 is hereinafter void. Search firms are essential to the recruitment and staffing efforts at Wyeth and we value the partnerships we have built with our preferred vendors. For this reason, Wyeth has established and regularly maintains a preferred vendor list. Please note that even preferred vendors need to have a written search agreement signed by the Vice President, Strategic Staffing at Wyeth in place for the specific position in order for a fee to be paid for any candidate referrals.Expected Travel Time: None Zip Code :US-PA-Collegeville Leading the way to a healthier world.